Isotopically Labeled Compounds
Medchemexpress LLC Sulbactam-d5 sodium | 1322625-44-4 | 99.9% | 500 UG
Sulbactam-d5 sodium is a deuterium-labeled form of Sulbactam sodium, a competitive, irreversible beta-lactamase inhibitor. It demonstrates antimicrobial activity against multidrug-resistant Acinetobacter calcoaceticus--Acinetobacter baumannii complex. Deuteration in drug molecules can impact pharmacokinetic and metabolic profiles, making this compound valuable for research.
- Functions as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Isotope-labeled compound
- Deuterium stable isotope-labeled inhibitor for in vivo cell experiments
- Applicable in therapeutic drug monitoring
Medchemexpress LLC Nonanoic acid-d17 | 130348-94-6 | 25 MG
Nonanoic acid-d17 is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. It significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ethylmalonic acid-d5 | 66311-22-6 | 98.1% | 137.15 | 1 MG
Ethylmalonic acid-d5 is a deuterium labeled short-chain organic dicarboxylic acid. It synergistically induces mitochondrial permeability transition with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. This compound can be used in the research of SCADD, EE, and other genetic metabolic diseases characterized by EMA accumulation.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled compound for pharmacokinetic and metabolic studies
- Inhibits mitochondrial creatine kinase activity
- Disrupts mitochondrial energy metabolism
Cambridge Isotope Laboratories EFSA-4 13C PAH Standard Mixture (13C 99%) in nonane 1 2 mL
EFSA-4 13C PAH Standard Mixture (13C 99%) in nonane 1 2 mL
Medchemexpress LLC Deoxycholic acid | 83-44-3 | 392.57 | 5 G
Deoxycholic acid (cholanoic acid) is a bile acid, a by-product of intestinal metabolism that activates the G protein-coupled bile acid receptor TGR5. It is for research use only.
- Activates G protein-coupled bile acid receptor TGR5
- Available in solid form
- Suitable for research applications
Medchemexpress LLC Benzocaine-(ethyl-d5) | 1219803-76-5 | 99.0% | 170.22 g/mol | C9H6D5NO2 | 10mg
Benzocaine-(ethyl-d5) is the deuterium labeled Benzocaine Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na channel with an IC50 of 0 8 mM tested with a potential of 30 mV
Medchemexpress LLC Propranolol-d7 (hydrochloride) | 1613439-56-7 | 98.5% | 5 MG
Propranolol-d7 (hydrochloride) | 1613439-56-7 | 98.5% | 5 MG
Medchemexpress LLC Ethylparaben-d4 | 1219795-53-5 | 99.6% | 5 MG
Ethylparaben-d4 is a deuterium-labeled Ethylparaben intended for research use only. This compound can function as a tracer or an internal standard for quantitative analysis using methods like NMR, GC-MS, or LC-MS. It exhibits high purity and specific storage requirements to maintain its stability.
- High purity of 99.6%
- Molecular weight of 170.20
- Solid, white to off-white appearance
- Store powder at -20°C for up to 3 years
- Store in solvent at -80°C for 6 months, or -20°C for 1 month
- Suitable for use as a tracer
- Functions as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
Medchemexpress LLC Fmoc-Pro-OH-13C5,15N | 1217452-48-6 | 343.33 | 5 MG
Fmoc-Pro-OH-13C5,15N is a 15N-labeled and 13C-labeled proline derivative, specifically an Fmoc-Pro-OH compound. It incorporates stable heavy isotopes of carbon and nitrogen, making it suitable for use as a tracer in drug development for quantitation and studying the impact of isotopic substitution on drug pharmacokinetics and metabolic profiles.
- 15N-labeled and 13C-labeled proline derivative
- Useful as a tracer in drug development
- Aids in quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- For research purposes only
Medchemexpress LLC L-Alanine-d7 | 74280-71-0 | 99.8% | 96.14 | 5 MG
L-Alanine-d7 is the deuterium-labeled version of L-Alanine. L-Alanine is a non-essential amino acid that plays a role in sugar and acid metabolism, boosts immunity, and provides energy for muscle tissue, the brain, and the central nervous system. This compound is used for research purposes only and is not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis using methods such as NMR, GC-MS, or LC-MS.
- Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-serine-2,3,3-d3 | 1414348-52-9 | 96.4% | 108.11 g/mol | C3H4D3NO3 | 1 MG
D-Serine-d3 is a deuterium-labeled form of the endogenous amino acid D-serine, provided as an isotopic reference standard for analytical and biochemical research. It is commonly used in mass spectrometry, tracer studies, and assays probing NMDA receptor-related neurotransmission and synaptic processes.
- Deuterium-labeled (d3) analogue suitable for isotope-dilution analyses.
- High purity (96.4%) for analytical reproducibility.
- Molecular weight 108.11 g/mol and formula C3H4D3NO3.
- Supplied in 1 mg quantity for standard preparation.
- Supports studies of NMDA receptor-mediated neurotransmission and synaptic plasticity.
Cayman Chemical DIclofenac-d4 500ug
An internal standard for the quantification of diclofenac by GC- or LC-MS
Medchemexpress LLC 2-bromopyridine-d4 | 70766-71-1 | 98.4% | 162.02 g/mol | C5D4BrN | 50mg
2-Bromopyridine-d4 is the deuterium labeled 2-Bromopyridin[1]
Cambridge Isotope Laboratories ETHYLENE (1,2-13C2, 99%), 0.1 L, 51915-19-6
ETHYLENE (1,2-13C2, 99%), 0.1 L, 51915-19-6
Sigma Aldrich Fine Chemicals Biosciences Benzylamine-15N 98 atom % 15N | 42927-57-1 | MFCD00190515 | 1G
Benzylamine-15N 98 atom % 15N | Purity: 99% (CP) | Mol Wt: 108.15 | 42927-57-1 | MFCD00190515 | 1G